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6-month RCT (n = 54) documented dose- and time-dependent increases in body glutathione stores, with the 1,000 mg/day group achieving 30-35% increases in erythrocyte, plasma, and lymphocyte GSH and a 260% increase in buccal mucosal cells

The study found significant decreases in State-Trait Anxiety scores and Pittsburgh Sleep Quality Index (PSQI) scores, indicating reduced stress and improved sleep latency

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